Ollier’s disease, or enchondromatosis, is a rare congenital disease of abnormal bone development due to cartilage overgrowth in the form of enchondromas, or benign, non-cancerous tumors. The limbs’ long bones and joint cartilage are affected by the disease, and the small bones and metatarsals of the hands and feet are common sites for the enchondromas to develop. The masses can also grow elsewhere in the body.
It is possible but not common for the tumors to become malignant, or cancerous. Most cases of Ollier’s disease remain benign and do not require treatment unless bone tissue is destroyed by quick-growing tumors. Then, the growths can be surgically removed.
The signs and indications in Ollier disease might be available during childbirth, yet regularly show up in the main decade of life. The principal side effect might be the presence of numerous hard masses (swellings) on a finger or a toe, a hilter kilter shortening of a limit with limping, or skeletal distortions which might be related to a hidden break. Enchondromas regularly happen in the appendage bones, particularly the bones of the hands and feet. Different bones that might be influenced incorporate the tibia, femur, fibula, humerus, pelvis, skull, ribs, and vertebrae.
The enchondromas may influence numerous bones and are normally lopsidedly dispersed, only or prevalently influencing one side of the body. Influenced bones are frequently abbreviated and disfigured. In a few, bone shortening might be the main perceptible manifestation. These bone shortenings are regularly connected with bone bowing and bending and may prompt restrictions in joint portability and muscle improvement.
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